A case of idiopathic bence jones proteinuria - Some notes on the clinical significance of bence jones proteinuria.
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چکیده
منابع مشابه
The outcome of idiopathic Bence Jones proteinuria.
The authors studied two patients with idiopathic Bence Jones proteinuria (BJP) that fulfill all the criteria proposed by Kyle and Greipp. None had evidence of overt multiple myeloma, of its variants, of primary systemic amyloidosis, or of other lymphoid tumors. In a patient with kappa type idiopathic BJP an elevation of a labelling index was found when an evolving myeloma developed 2 years late...
متن کاملBence Jones proteinuria in multiple sclerosis.
We report our findings of Bence Jones proteins (monoclonal free light chains of immunoglobulins) in concentrated urines of patients with multiple sclerosis, by using agarose electrophoresis and immunofixation. The lack of such findings in urines from healthy subjects and patients with other neurological disorders should stimulate further investigation.
متن کاملBence Jones proteinuria and myeloma kidney.
Bence-Jones proteinuria refers to urinary excretion of monoclonal light chains. It results from exclusive production of one light chain, or the unbalanced synthesis of heavy and light chains, with the latter being in excess. Free Kor A-light chains are therefore excreted alone or in addition to complete immunoglobulin molecules carrying the same light chain type. Free light chains are low molec...
متن کاملacute plasma cell leukemia associated with bence-jones proteinuria: a case report
acute plasma cell leukemia with bence-jones proteinuria is reported in a 60 year old lranien male with a 25 day history of acute onset of fever. weakness, weight loss, diarrhea and bloody stools. the patient was noted to be cachectic and anemic. he had purpuric and petechial skin lesions, generalized lymphadenopathy and splenomegaly. up to 80% immature plasma cells were present in the periphera...
متن کاملMetabolism of Bence Jones Proteins.
Bence Jones proteins are molecules of about 40,000 mol wt present in the urine of many patients with plasma cell malignancy. These microglobulins, which are synthesized in plasma-cell tumors (1, 2), share many immunochemical and physicochemical features with the larger 6.6 S y-globulins. That Bence Jones proteins are similar to or identical with components of the larger y-globulins has been sug...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 1985
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.74.462